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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Capillary electrophoresis–mass spectrometry ： ウィキペディア英語版 Capillary electrophoresis–mass spectrometry Capillary electrophoresis–mass spectrometry (CE-MS) is an analytical chemistry technique formed by the combination of the liquid separation process of capillary electrophoresis with mass spectrometry. CE-MS combines advantages of both CE and MS to provide high separation efficiency and molecular mass information in a single analysis. It has high resolving power and sensitivity, requires minimal volume and can analyze at high speed. Ions are typically formed by electrospray ionization, but they can also be formed by matrix-assisted laser desorption/ionization or other ionization techniques. It has applications in basic research in proteomics and quantitative analysis of biomolecules as well as in clinical medicine. Since its introduction in 1987, new developments and application has made CE-MS powerful separation and identification technique. Use of CE-MS has increased for protein and peptides analysis and other biomolecules. Understanding of CE, the interface setup, ionization technique and mass detection system is important to tackle problems while coupling capillary electrophoresis to mass spectrometry. ==History== The original interface between capillary zone electrophoresis and mass spectrometry was developed in 1987〔Schmitt-Kopplin, P., Frommberger, M.(2003).Capillary electrophoresis – mass spectrometry: 15 years of developments and applications. Electrophoresis, 24, 3837-3867.〕 by Richard D. Smith and coworkers at Pacific Northwest National Laboratory, and who also later were involved in development of interfaces with other CE variants, including capillary isotachophoresis and capillary isoelectric focusing. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Capillary electrophoresis–mass spectrometry」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.